The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes

Author:

Hove-Madsen Leif,Llach Anna,Molina Cristina E.,Prat-Vidal Cristina,Farré Jordi,Roura Santiago,Cinca Juan

Publisher

Elsevier BV

Subject

Pharmacology

Reference31 articles.

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2. Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity;Burashnikov;Circulation,2003

3. Effects of cetirizine on the delayed K+ currents in cardiac cells: comparison with terfenadine;Carmeliet;Br. J. Pharmacol.,1998

4. Blockade of multiple human cardiac potassium currents by the antihistamine terfenadine: possible mechanism for terfenadine-associated cardiotoxicity;Crumb;Mol. Pharmacol.,1995

5. Cardiac K+ channels and drug-acquired long QT syndrome;Drici;Therapie,2000

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