Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics-Reference-Cited by-同舟云学术

Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics

Published:2022-11 Issue: Volume:935 Page:175331
ISSN:0014-2999
Container-title:European Journal of Pharmacology
language:en
Short-container-title:European Journal of Pharmacology

Author:

Wang Jiawei^ORCID,Wen Jianxia,Ma Xiao,Yang Ju,Zhang Zhao,Xie Shuying,Wei Shizhang,Jing Manyi,Li Haotian,Lang Liwei,Zhou Xuelin,Zhao Yanling

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology

Reference51 articles.

1. Hepatoprotective effects of diosmin and/or sildenafil against cholestatic liver cirrhosis: the role of Keap-1/Nrf-2 and P38-MAPK/NF-κB/iNOS signaling pathway;Ali;Food Chem. Toxicol.,2018

2. Role of protein kinase C isoforms in bile formation and cholestasis;Anwer;Hepatology,2014

3. Sequential activation of classic PKC and estrogen receptor α is involved in estradiol 17ß-D-glucuronide-induced cholestasis;Barosso;PLoS One,2012

4. Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer;Bartolacci;Nat. Commun.,2022

5. Intrahepatic cholestasis of pregnancy: changes in maternal-fetal bile acid balance and improvement by ursodeoxycholic acid;Brites;Ann. Hepatol.,2002

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Metabolomics and serum pharmacochemistry combined with network pharmacology uncover the potential effective ingredients and mechanisms of Yin-Chen-Si-Ni Decoction treating ANIT-induced cholestatic liver injury;Journal of Ethnopharmacology;2024-12

2. Paeoniflorin inhibited GSDMD to alleviate ANIT-induced cholestasis via pyroptosis signaling pathway;Phytomedicine;2024-11

3. Exploring the Potential Mechanisms of Action of Gentiana Veitchiorum Hemsl. Extract in the Treatment of Cholestasis using UPLC-MS/MS, Systematic Network Pharmacology, and Molecular Docking;Combinatorial Chemistry & High Throughput Screening;2024-08

4. Si-Wu-Tang alleviates metabolic dysfunction-associated fatty liver disease by inhibiting ACSL4-mediated arachidonic acid metabolism and ferroptosis in MCD diet-fed mice;Chinese Medicine;2024-06-06

5. Integrated phytochemistry and network pharmacology analysis to reveal effective substances and mechanisms of Bushen Quhan Zhiwang decoction in the treatment of rheumatoid arthritis;Journal of Ethnopharmacology;2024-05