A “locked-on,” constitutively active mutant of the adenosine A1 receptor

Author:

de Ligt Rianne A.F.,Rivkees Scott A.,Lorenzen Anna,Leurs Rob,IJzerman Ad P.

Publisher

Elsevier BV

Subject

Pharmacology

Reference24 articles.

1. The effect of mutations in the DRY motif on the constitutive activity and structural instability of the histamine H2 receptor;Alewijnse;Mol. Pharmacol.,2000

2. Site-directed mutagenesis of the human A1 adenosine receptor: influences of acidic and hydroxy residues in the first four transmembrane domains on ligand binding;Barbhaiya;Mol. Pharmacol.,1996

3. The allosteric enhancer, PD81,723, stabilizes human A1 adenosine receptor coupling to G proteins;Bhattacharya;Biochim. Biophys. Acta,1995

4. Optimization and simplification of expression cloning in eukaryotic vector/host systems;Brakenhoff;Anal. Biochem.,1994

5. Allosteric enhancement of adenosine A1 receptor binding and function by 2-amino-3-benzoylthiophenes;Bruns;Mol. Pharmacol.,1990

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