The anti-pruritic efficacy of TS-022, a prostanoid DP1 receptor agonist, is dependent on the endogenous prostaglandin D2 level in the skin of NC/Nga mice

Author:

Sugimoto Masanori,Arai Iwao,Futaki Nobuko,Hashimoto Yuki,Sakurai Takanobu,Honma Yusuke,Nakaike Shiro

Publisher

Elsevier BV

Subject

Pharmacology

Reference33 articles.

1. Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis;Arai;Eur. J. Pharmacol.,2004

2. Effects of TS-022, a newly developed prostanoid DP1 receptor agonist, on experimental pruritus, cutaneous barrier disruptions and atopic dermatitis in mice;Arai;Eur. J. Pharmacol.,2007

3. Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles;Chan;J. Pharmacol. Exp. Ther.,1999

4. Immunomodulation by eicosanoids and anti-inflammatory drugs;Goodwin;Curr. Opin. Immunol.,1989

5. Comparison of analgesic and anti-inflammatory activity of meloxicam gel with diclofenac and piroxicam gels in animal models: pharmacokinetic parameters after topical application;Gupta;Skin Pharmacol. Appl. Skin Physiol.,2002

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