Characterization of the interaction of the novel antihypertensive etamicastat with human dopamine-β-hydroxylase: Comparison with nepicastat

Author:

Bonifácio Maria João,Sousa Filipa,Neves Marco,Palma Nuno,Igreja Bruno,Pires Nuno Miguel,Wright Lyndon C.,Soares-da-Silva Patrício

Publisher

Elsevier BV

Subject

Pharmacology

Reference25 articles.

1. Etamicastat, a novel dopamine β-hydroxylase inhibitor: tolerability, pharmacokinetics, and pharmacodynamics in patients with hypertension;Almeida;Clin. Ther.,2013

2. Dopamine β-monooxygenase: mechanism, substrates and inhibitors;Beliaev;Curr. Enzyme Inhib.,2009

3. Synthesis and biological evaluation of novel, peripherally selective chromanyl imidazolethione-based inhibitors of dopamine beta-hydroxylase;Beliaev;J. Med. Chem.,2006

4. Bonifácio, M.J., Igreja, B., Wright, L., Soares-da-Silva, P., 2009. Kinetic studies on the inhibition of dopamine-ß-hydroxylase by BIA 5-453. pA2 online 7, 050P (abstract).

5. Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis;Copeland,2000

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