Desloratadine citrate disodium injection, a potent histamine H1 receptor antagonist, inhibits chemokine production in ovalbumin-induced allergic rhinitis guinea pig model and histamine-induced human nasal epithelial cells via inhibiting the ERK1/2 and NF-kappa B signal cascades

Author:

Chen Meiling,Xu Shuhong,Zhou Peipei,He Guangwei,Jie Qiong,Wu Yulin

Funder

China Pharmaceutical University

Publisher

Elsevier BV

Subject

Pharmacology

Reference27 articles.

1. Allergic rhinitis and its pharmacology;Al Suleimani;Pharmacol. Ther.,2007

2. Antiallergic anti-inflammatory effects of H1-antihistamines in humans;Assanasen;Clin. Allergy Immunol.,2002

3. Validation of guinea pig model of allergic rhinitis by oral and topical drugs;Bahekar;Int. Immunopharmacol.,2008

4. Pathogenesis of allergic rhinitis;Baraniuk;J. Allergy Clin. Immunol.,1997

5. MCP-1 and RANTES are mediators of acute and chronic inflammation;Conti;Allergy Asthma Proc.,2001

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