Anti-diabetic drug metformin dilates retinal blood vessels through activation of AMP-activated protein kinase in rats
Author:
Funder
Kitasato University Research Grant for Young Researchers
JSPS
Publisher
Elsevier BV
Subject
Pharmacology
Reference40 articles.
1. The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level;Ben;Oncogene,2008
2. AMP-activated protein kinase impairs endothelial actin cytoskeleton assembly by phosphorylating vasodilator-stimulated phosphoprotein;Blume;J. Biol. Chem.,2007
3. Intravenous AICAR during hyperinsulinemia induces systemic hemodynamic changes but has no local metabolic effect;Bosselaar;J. Clin. Pharmacol.,2011
4. Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside in the muscle microcirculation increases nitric oxide synthesis and microvascular perfusion;Bradley;Arterioscler. Thromb. Vasc. Biol.,2010
5. Metformin relaxes rat tail artery by repolarization and resultant decreases in Ca2+ influx and intracellular [Ca2+];Chen;J. Hypertens.,1997
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