Propofol inhibits hERG K+ channels and enhances the inhibition effects on its mutations in HEK293 cells
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Pharmacology
Reference54 articles.
1. Anaesthetic induced ventricular tachyarrhythmia in Jervell and Lange-Nielsen syndrome;Adu-Gyam;Can. J. Anaesth.,1991
2. Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanisms;Anderson;Circulation,2006
3. Metabolic acidosis, rhabdomyolysis, and cardiovascular collapse after prolonged propofol infusion;Cannon;J. Neurosurg.,2001
4. Torsade de pointes after astemizole overdose;Craft;Br. Med. J.,1986
5. Long-term propofol infusion and cardiac failure in adult head-injured patients;Cremer;Lancet,2001
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Comparison of the effects of propofol and alfaxalone on the electrocardiogram of dogs, with particular reference to QT interval;Frontiers in Veterinary Science;2024-01-08
2. Prediction of anesthetic torsadogenicity using a human ventricular cell model;Journal of Anesthesia;2023-07-31
3. Elevation of propofol sensitivity of cardiac I Ks channel by KCNE1 polymorphism D85N;British Journal of Pharmacology;2021-04-24
4. Cardiac hERG K+ Channel as Safety and Pharmacological Target;Pharmacology of Potassium Channels;2021
5. A computational analysis of the effect of sevoflurane in a human ventricular cell model of long QT syndrome: Importance of repolarization reserve in the QT-prolonging effect of sevoflurane;European Journal of Pharmacology;2020-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3