Celastrol, which targets IL-2/CD25 binding inhibition, induces T cell-mediated antitumor activity in melanoma
Author:
Funder
Ministry of Education, Science and Technology
Catholic University of Korea
National Research Foundation of Korea
Publisher
Elsevier BV
Subject
Pharmacology
Reference46 articles.
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2. Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ;Astry;Clin Immunol,2015
3. Editorial: novel combination therapies for the treatment of solid cancers;Ayoub;Front. Oncol.,2021
4. Celastrol inhibits colorectal cancer cell proliferation and migration through suppression of MMP3 and MMP7 by the PI3K/AKT signaling pathway;Bufu;Anti Cancer Drugs,2018
5. The antitumor effect induced by an IL-2 'no-alpha' mutein depends on changes in the CD8(+) T lymphocyte/Treg cell balance;Carmenate;Front. Immunol.,2022
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