Isoorientin reverses lung cancer drug resistance by promoting ferroptosis via the SIRT6/Nrf2/GPX4 signaling pathway

Author:

Feng SenlingORCID,Li Yuting,Huang Hanhui,Huang Hongliang,Duan Yingying,Yuan Zhongwen,Zhu Wenting,Mei Zhengrong,Luo Lianxiang,Yan Pengke

Publisher

Elsevier BV

Subject

Pharmacology

Reference52 articles.

1. Ferroptosis and cancer: mitochondria meet the "Iron Maiden" cell death;Battaglia;Cells,2020

2. Iron, ferroptosis, and new insights for prevention in acute kidney injury;Borawski;Adv. Med. Sci.,2020

3. SIRT6 silencing overcomes resistance to sorafenib by promoting ferroptosis in gastric cancer;Cai;Biochem. Biophys. Res. Commun.,2021

4. Ferroptosis in liver diseases: an overview;Capelletti;Int. J. Mol. Sci.,2020

5. Pathological transition as the arising mechanism for drug resistance in lung cancer;Chen;Cancer Commun. (Lond.),2019

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