Hepatic glucagon receptor binding and glucose-lowering in vivo by peptidyl and non-peptidyl glucagon receptor antagonists

Author:

Dallas-Yang Qing,Shen Xiaolan,Strowski Mathias,Brady Edward,Saperstein Richard,Gibson Raymond E.,Szalkowski Deborah,Qureshi Sajjad A.,Candelore Mari Rios,Fenyk-Melody Judith E.,Parmee Emma R.,Zhang Bei B.,Jiang Guoqiang

Publisher

Elsevier BV

Subject

Pharmacology

Reference32 articles.

1. Role of glucagon in maintenance of euglycemia in fed and fasted rats;Brand;Am. J. Physiol.,1995

2. Evidence for a major role for glucagon in regulation of plasma glucose in conscious, nondiabetic, and alloxan-induced diabetic rabbits;Brand;Diabetes,1996

3. Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycaemia in moderately streptozotocin-diabetic rats;Brand;Diabetologia,1994

4. Molecular and cellular aspects of the glucagon receptor: role in diabetes and metabolism;Burcelin;Diabetes Metab.,1996

5. Characterization of a novel, non-peptidyl antagonist of the human glucagon receptor;Cascieri;J. Biol. Chem.,1999

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