Morphine-6-glucuronide induces contraction of the ileal circular muscle more potently than morphine in mice

Author:

Iwata Hiroki,Tsuchiya Shizuko,Ueno Koichi,Nakamura Tomonori,Yano Shingo

Publisher

Elsevier BV

Subject

Pharmacology

Reference15 articles.

1. Further evidence that morphine-6β-glucuronide is a more potent opioid agonist than morphine;Frances;J. Pharmacol. Exp. Ther.,1992

2. Morphine-3-glucuronide may functionally antagonize morphine-6-glucuronide induced antinociception and ventilatory depression in the rat;Gong;Pain,1992

3. Morphine pharmacokinetics and metabolism in humans. enterohepatic cycling and relative contribution of metabolites to active opioid concentrations;Hasselstrom;Clin. Pharmacokinet.,1993

4. Control of non-adrenergic non-cholinergic reflex motor responses in circular muscle of guinea-pig small intestine by Met-enkephalin;Ivancheva;Auton. Autacoid Pharmacol.,2002

5. Morphine leads to contraction of the ileal circular muscle via inhibition of the nitrergic pathway in mice;Iwata;Eur. J. Pharmacol.,2007

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2. Metabolism studies of casticin in rats using HPLC-ESI-MSn;Biomedical Chromatography;2012-03-08

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