Evaluation of the effects of RP5063, a novel, multimodal, serotonin receptor modulator, as single-agent therapy and co-administrated with sildenafil, bosentan, and treprostinil in a monocrotaline-induced pulmonary arterial hypertension rat model-Reference-Cited by-同舟云学术

Evaluation of the effects of RP5063, a novel, multimodal, serotonin receptor modulator, as single-agent therapy and co-administrated with sildenafil, bosentan, and treprostinil in a monocrotaline-induced pulmonary arterial hypertension rat model

Published:2018-05 Issue: Volume:827 Page:159-166
ISSN:0014-2999
Container-title:European Journal of Pharmacology
language:en
Short-container-title:European Journal of Pharmacology

Author:

Bhat Laxminarayan,Hawkinson Jon,Cantillon Marc,Reddy Dasharatha G.,Bhat Seema R.,Laurent Charles-E.,Bouchard Annie,Biernat Marzena,Salvail Dany

Funder

Reviva Pharmaceuticals, Inc

Pharmaceuticals

Publisher

Elsevier BV

Subject

Pharmacology

Reference41 articles.

1. Formation of plexiform lesions in experimental severe pulmonary arterial hypertension;Abe;Circulation,2010

2. Sildenafil in the treatment of pulmonary hypertension;Barnett;Vasc. Health Risk Manag.,2006

3. An evaluation of long-term survival from time of diagnosis in pulmonary arterial hypertension from the REVEAL registry;Benza;Chest,2012

4. RP5063, a novel, multimodal, serotonin receptor modulator, prevents monocrotaline-induced pulmonary arterial hypertension in rats;Bhat;Eur. J. Pharmacol.,2017

5. RP5063, a novel, multimodal, serotonin receptor modulator, prevents Sugen 5416-hypoxia– induced pulmonary arterial hypertension in rats;Bhat;Eur. J. Pharmacol.,2017

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