The proconvulsant effects of the GABAA α5 subtype-selective compound RY-080 may not be α5-mediated
Author:
Publisher
Elsevier BV
Subject
Pharmacology
Reference25 articles.
1. Regional differences in the inhibition of mouse in vivo [3H]Ro 15–1788 binding reflect selectivity for α1 versus α2 and α3 subunit-containing GABAA receptors;Atack;Neuropsychopharmacology,1999
2. In vivo labelling of α5 subunit-containing GABAA receptors using the selective radioligand [3H]L-655,708;Atack;Neuropharmacology,2005
3. Effects of hippocampal injections of a novel ligand selective for the α5β2γ2 subunits of the GABA/benzodiazepine receptor on Pavlovian conditioning;Bailey;Neurobiol. Learn. Mem.,2002
4. An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA α5 receptors with cognition enhancing properties;Chambers;J. Med. Chem.,2004
5. Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the α5 subunit of the GABAA receptor;Collinson;J. Neurosci.,2002
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4. Exploring the genomic basis of pharmacoresistance in epilepsy: an integrative analysis of large-scale gene expression profiling studies on brain tissue from epilepsy surgery;Human Molecular Genetics;2011-08-18
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