KAG-308, a newly-identified EP4-selective agonist shows efficacy for treating ulcerative colitis and can bring about lower risk of colorectal carcinogenesis by oral administration
Author:
Publisher
Elsevier BV
Subject
Pharmacology
Reference45 articles.
1. An experiment to determine the active therapeutic moiety of sulphasalazine;Azad;Lancet,1977
2. High resolution colonoscopy in live mice;Becker;Nat. Protoc.,2006
3. In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy;Becker;Gut,2005
4. Prostaglandin E(2) stimulates rat and human colonic mucin exocytosis via the EP(4) receptor;Belley;Gastroenterology,1999
5. 5-aminosalicylate is not chemoprophylactic for colorectal cancer in IBD: a population based study;Bernstein;Am. J. Gastroenterol.,2011
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