Pharmacological activation of cannabinoid 2 receptor attenuates inflammation, fibrogenesis, and promotes re-epithelialization during skin wound healing

Author:

Wang Lin-Lin,Zhao Rui,Li Jiao-Yong,Li Shan-Shan,Liu Min,Wang Meng,Zhang Meng-Zhou,Dong Wen-Wen,Jiang Shu-Kun,Zhang Miao,Tian Zhi-Ling,Liu Chang-Sheng,Guan Da-Wei

Funder

National Natural Science Foundation of China

Shenyang Scientific and Technological Plan

Anshan Scientific and Technological Plan

Publisher

Elsevier BV

Subject

Pharmacology

Reference57 articles.

1. The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis;Akhmetshina;Arthritis Rheumatol.,2009

2. Cannabinoid receptor type-2 stimulation, blockade, and deletion alter the vascular inflammatory responses to traumatic brain injury;Amenta;J. Neuroinflamm.,2014

3. Fibroblasts/myofibroblasts that participate in cutaneous wound healing are not derived from circulating progenitor cells;Barisic-Dujmovic;J. Cell. Physiol.,2010

4. The many faces of interleukin-6: the role of IL-6 in inflammation, vasculopathy, and fibrosis in systemic sclerosis;Barnes;Int. J. Rheumatol.,2011

5. Epithelial mesenchymal transition: a double-edged sword;Barriere;Clin. Transl. Med.,2015

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