(2S,4S)-4-Fluoro-1-{[(2-hydroxy-1,1-dimethylethyl)amino]acetyl}-pyrrolidine-2-carbonitrile monobenzenesulfonate (TS-021) is a selective and reversible dipeptidyl peptidase IV inhibitor
Author:
Publisher
Elsevier BV
Subject
Pharmacology
Reference35 articles.
1. Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in noninsulin-dependent diabetes mellitus;Ahrén;J. Clin. Endocrinol. Metab.,1997
2. Improved glucose tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice;Ahrén;Eur J Pharmacol.,2000
3. Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4-week study period in type 2 diabetes;Ahrén;Diab. Care,2002
4. Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes;Ahrén;Diab. Care,2004
5. Inhibition of human elastase from polymorphonuclear leucocytes by gold sodium thiomalate and pentosan polysulfate (SP-54);Baici;Biochem. Pharmacol.,1981
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Recent Medicinal Chemistry Approach for the Development of Dipeptidyl Peptidase IV Inhibitors;Current Medicinal Chemistry;2021-06-10
2. Copper-catalyzed [3 + 2]-cycloaddition of α-halonitroalkenes with azomethine ylides: facile synthesis of multisubstituted pyrrolidines and pyrroles;Organic & Biomolecular Chemistry;2021
3. CMD-05, a novel promising clinical anti-diabetic drug candidate, in vivo and vitro studies;Scientific Reports;2017-04-13
4. Sixteen-Years of Clinically Relevant Dipeptidyl Peptidase-IV (DPP-IV) Inhibitors for Treatment of Type-2 Diabetes: A Perspective;Current Medicinal Chemistry;2014-10-23
5. Combination of TS-021 with metformin improves hyperglycemia and synergistically increases pancreatic β-cell mass in a mouse model of type 2 diabetes;Life Sciences;2011-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3