Involvement of tryptophan W276 and of two surrounding amino acid residues in the high constitutive activity of the ghrelin receptor GHS-R1a
Author:
Publisher
Elsevier BV
Subject
Pharmacology
Reference30 articles.
1. CCK-B/Gastrin receptor transmembrane domain mutations selectively alter synthetic agonist efficacy without affecting the activity of endogenous peptides;Blaker;Mol. Pharmacol.,2000
2. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor;Cherezov;Science,2007
3. Over-expression of the truncated ghrelin receptor polypeptide attenuates the constitutive activation of phosphatidylinositol-specific phospholipase C by ghrelin receptors but has no effect on ghrelin-stimulated extracellular signal-regulated kinase 1/2 activity
4. A hydrophobic cluster between transmembrane helices 5 and 6 constrains the thyrotropin-releasing hormone receptor in an inactive conformation;Colson;Mol. Pharmacol.,1998
5. Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues;Feighner;Mol. Endocrinol.,1998
Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Sodium is a negative allosteric regulator of the ghrelin receptor;Cell Reports;2023-04
2. G protein‐coupled receptor interactions and modification of signalling involving the ghrelin receptor, GHSR1a;Journal of Neuroendocrinology;2021-12-20
3. Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor;Nature Communications;2021-08-20
4. Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor;2021-06-10
5. Buzhongyiqi Decoction Protects Against Loperamide-Induced Constipation by Regulating the Arachidonic Acid Pathway in Rats;Frontiers in Pharmacology;2020-04-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3