Effective block by pirfenidone, an antifibrotic pyridone compound (5-methyl-1-phenylpyridin-2[H-1]-one), on hyperpolarization-activated cation current: An additional but distinctive target

Author:

Chang Wei-Ting,Ragazzi Eugenio,Liu Ping-Yen,Wu Sheng-Nan

Funder

National Cheng Kung University

Publisher

Elsevier BV

Subject

Pharmacology

Reference48 articles.

1. Identifier NCT04282902, A Study to Evaluate the Efficacy and Safety of Pirfenidone with Novel Coronavirus Infection,2020

2. Pirfenidone is a cardioprotective drug: mechanisms of action and preclinical evidence;Aimo;Pharmacol. Res.,2020

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4. High-resolution CT change over time in patients with idiopathic pulmonary fibrosis on antifibrotic treatment;Balestro;J. Clin. Med.,2019

5. A caveolin-binding domain in the HCN4 channels mediates functional interaction with caveolin proteins;Barbuti;J. Mol. Cell. Cardiol.,2012

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