Significant combination of Aβ aggregation inhibitory and neuroprotective properties in silico, in vitro and in vivo by bis(propyl)-cognitin, a multifunctional anti-Alzheimer’s agent-Reference-Cited by-同舟云学术

Significant combination of Aβ aggregation inhibitory and neuroprotective properties in silico, in vitro and in vivo by bis(propyl)-cognitin, a multifunctional anti-Alzheimer’s agent

Published:2020-06 Issue: Volume:876 Page:173065
ISSN:0014-2999
Container-title:European Journal of Pharmacology
language:en
Short-container-title:European Journal of Pharmacology

Author:

Hu Shengquan,Xian Yanfang,Fan Yubo,Mak Shinghung,Wang Jiajun,Tang Jing,Pang Yuanping,Pi Rongbiao,Tsim Karl Wahkeung,Liu Fufeng,Lin Zhixiu,Han Yifan

Funder

Council of Hong Kong

University of Macau

ITSP-Guangdong–Hong Kong Technology Cooperation

Shenzhen

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology

Reference51 articles.

1. Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3beta pathway in the mouse hippocampus;Ali;J. Pineal Res.,2015

2. beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease;Arias;Exp. Neurol.,2002

3. Cumulative, additive benefits of memantine-donepezil combination over component monotherapies in moderate to severe Alzheimer's dementia: a pooled area under the curve analysis;Atri;Alzheimer's Res. Ther.,2015

4. Two-step nucleation of amyloid fibrils: omnipresent or not?;Auer;J. Mol. Biol.,2012

5. Clusterin binds to abeta1-42 oligomers with high affinity and interferes with peptide aggregation by inhibiting primary and secondary nucleation;Beeg;J. Biol. Chem.,2016

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Multifunctional Inhibitors of Cholinesterases for the Therapy of Alzheimer’s Disease (A Review);Russian Journal of General Chemistry;2023-12

2. Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer’s Disease;International Journal of Molecular Sciences;2023-01-24

3. Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer’s Activity Profile;Molecules;2022-02-04

4. Protection against H₂O₂-evoked toxicity in HT22 hippocampal neuronal cells by geissoschizine methyl ether via inhibiting ERK pathway;Translational Neuroscience;2022-01-01

5. Exploration of Potent Multi-target-directed-ligands as Anti-alzheimer’s Disease Agents: A Moiety Based Review;Mini-Reviews in Medicinal Chemistry;2021-12