Recombinant human ciliary neurotrophic factor reduces weight partly by regulating nuclear respiratory factor 1 and mitochondrial transcription factor A

Author:

Liu Qing-Shan,Wang Qiu-Juan,Du Guan-Hua,Zhu Shen-Yin,Gao Mei,Zhang Li,Zhu Jun-Ming,Cao Jian-Feng

Publisher

Elsevier BV

Subject

Pharmacology

Reference24 articles.

1. PGC-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells;Andersson;Mol. Cell. Biol.,2001

2. Skeletal muscle overexpression of nuclear respiratory factor 1 increases glucose transport capacity;Baar;FASEB J.,2003

3. Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis;Bergeron;Am. J. Physiol.: Endocrinol. Metab.,2001

4. Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weights, and improves metabolic control in diet-induced obese and UCP1-DTA mice;Bluher;Diabetes,2004

5. Metabotrophic potential of neurotrophins: implication in obesity and related diseases?;Chaldakov;Med. Sci. Monit.,2003

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