The cordycepin derivative IMM-H007 improves endothelial dysfunction by suppressing vascular inflammation and promoting AMPK-dependent eNOS activation in high-fat diet-fed ApoE knockout mice

Author:

Wang Min-jie,Peng Xue-ying,Lian Ze-qin,Zhu Hai-bo

Funder

National Natural Science Foundation of China

CAMS Initiative for Innovative Medicine

The Drug Innovation Major Project

National Sciences and Technology Major Project

Institute of Materia Medica, CAMS & PUMC

Publisher

Elsevier BV

Subject

Pharmacology

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4. nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines;De Caterina;J. Clin. Invest.,1995

5. Endothelial function and dysfunction: testing and clinical relevance;Deanfield;Circulation,2007

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