Structure-activity relationship studies on (4-acylpyrrol-2-yl)alkanoic acids as inhibitors of the cytosolic phospholipase A2: Variation of the alkanoic acid substituent, the acyl chain and the position of the pyrrole nitrogen
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
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1. Passerini/Tsuji-Trost Strategy towards Pyrrole Derivatives;European Journal of Organic Chemistry;2017-08-04
2. Pyrrole alkanoic acid derivatives as nuisance inhibitors of microsomal prostaglandin E2 synthase-1;European Journal of Medicinal Chemistry;2012-02
3. Phospholipase A2 Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention;Chemical Reviews;2011-09-12
4. ChemInform Abstract: Structure-Activity Relationship Studies on (4-Acylpyrrol-2-yl)alkanoic Acids as Inhibitors of the Cytosolic Phospholipase A2: Variation of the Alkanoic Acid Substituent, the Acyl Chain, and the Position of the Pyrrole Nitrogen.;ChemInform;2010-06-24
5. Thermodynamic characterization of cytosolic phospholipase A2 alpha inhibitors;Analytical Biochemistry;2008-12
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