Validation of a DNA Methylation-Mutation Urine Assay to Select Patients with Hematuria for Cystoscopy

Author:

van Kessel Kim E.M.1,Beukers Willemien1,Lurkin Irene1,Ziel-van der Made Angelique1,van der Keur Kirstin A.1,Boormans Joost L.2,Dyrskjøt Lars3,Márquez Mirari4,Ørntoft Torben F.3,Real Francisco X.56,Segersten Ulrika7,Malats Núria4,Malmström Per-Uno7,Van Criekinge Wim89,Zwarthoff Ellen C.1

Affiliation:

1. Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands

2. Department of Urology, Erasmus Medical Center, Rotterdam, The Netherlands

3. Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark

4. Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Centre, Madrid

5. Epithelial Carcinogenesis Group, Spanish National Cancer Research Centre, Madrid

6. Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain

7. Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

8. MDxHealth, Inc., Irvine, California

9. Laboratory of Bioinformatics and Computational Genomics, Ghent University, Belgium

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Urology

Reference27 articles.

1. The significance of adult hematuria: 1,000 hematuria evaluations including a risk-benefit and cost-effectiveness analysis;Mariani;J Urol,1989

2. Richtlijn Hematurie. Nederlandse Vereniging voor Urologie 2010. Available at http://www.kwaliteitskoepel.nl/assets/structured-files/NVU/Hematurie.pdf. Accessed September 1, 2016.

3. Association between smoking and risk of bladder cancer among men and women;Freedman;JAMA,2011

4. Diagnosis, evaluation and follow-up of asymptomatic microhematuria (AMH) in adults: AUA guideline;Davis;J Urol,2012

5. GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase no. 11. International Agency for Research on Cancer 2013. Available at http://globocan.iarc.fr. Accessed September 1, 2016.

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