Structure–activity relationship and role of oxygen in the potential antitumour activity of fluoroquinolones in human epithelial cancer cells

Author:

Perucca Paola,Savio Monica,Cazzalini Ornella,Mocchi Roberto,Maccario Cristina,Sommatis Sabrina,Ferraro Daniela,Pizzala RobertoORCID,Pretali Luca,Fasani Elisa,Albini Angelo,Stivala Lucia Anna

Funder

Alma Mater Ticinensis Foundation

Publisher

Elsevier BV

Subject

Radiology, Nuclear Medicine and imaging,Biophysics,Radiological and Ultrasound Technology,Radiation

Reference48 articles.

1. The fluoroquinolone antibacterials: past, present and future perspectives;Appelbaum;Int. J. Antimicrob. Agents,2000

2. Fluoroquinolone antimicrobials: singlet oxygen, superoxide and phototoxicity;Martínez;Photochem. Photobiol.,1998

3. Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes;Shen;J. Biol. Chem.,1989

4. DNA topoisomerases: essential enzymes and lethal targets;Chen;Annu. Rev. Pharmacol. Toxicol.,1994

5. Photogenotoxicity of fluoroquinolones in Chinese hamster V79 cells: dependency on active topoisomerase II;Snyder;Photochem. Photobiol.,1999

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