Effects of tizanidine1Sirdalud is the trade name for tizanidine, manufactured by SANDOZ-WANDER PHARMA Bern, Switzerland.1 administration on precipitated opioid withdrawal signs in rats2The experimental protocol and procedures have been performad according to the regulations of Italian law: D.L. no. 116, 27/01/1992 and with the approval of the local University Committee on laboratory animals.2

Author:

Pinelli A,Trivulzio S,Spezia R

Publisher

Elsevier BV

Subject

Pharmacology (medical),Psychiatry and Mental health,Pharmacology,Toxicology

Reference54 articles.

1. Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine;Aghajanian;Nature,1978

2. The effect of some α2-adrenoceptor agonists and antagonists on gastrointestinal transit in mice: Influence of morphine, castor oil and glucose;Ali;Clin. Exp. Pharmacol. Physiol.,1993

3. Do presynaptic opiate receptors and α-adrenoceptors alter acetylcholine release from a sympathetic ganglion by a similar mechanism?;Araujo;Eur. J. Pharmacol.,1987

4. Armitage, P., 1991. Statistica Medica X Edizione. Feltrinelli, Milano, pp. 296–339; 382–394; 402–412.

5. Diversity of agents that modify opioid tolerance, physical dependence, abstinence syndrome and self-administrative behaviour;Bhargava;Pharmacol. Rev.,1994

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