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Shedding light on metabotropic glutamate receptors using optogenetics and photopharmacology

Published:2018-02 Issue: Volume:38 Page:8-15
ISSN:1471-4892
Container-title:Current Opinion in Pharmacology
language:en
Short-container-title:Current Opinion in Pharmacology

Author:

Goudet Cyril,Rovira Xavier,Llebaria Amadeu^ORCID

Funder

Agence Nationale de la Recherche

Fondation Recherche Médicale

Centre National de la Recherche Scientifique, the Spanish Ministry of Economy, Industry Competitiveness

MINECO

European Regional Development Fund

Catalan Government

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference59 articles.

1. Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors;Pin;Pharmacol Ther,2003

2. Orthosteric versus allosteric GPCR activation: the great challenge of group-III mGluRs;Flor;Biochem Pharmacol,2012

3. Practical strategies and concepts in GPCR allosteric modulator discovery: recent advances with metabotropic glutamate receptors;Lindsley;Chem Rev,2016

4. Metabotropic glutamate receptors: from the workbench to the bedside;Nicoletti;Neuropharmacology,2011

5. Exciting times beyond the brain: metabotropic glutamate receptors in peripheral and non-neural tissues;Julio-Pieper;Pharmacol Rev,2011

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4. Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations;Cell Reports;2021-08

5. International Union of Basic and Clinical Pharmacology. CXI. Pharmacology, Signaling, and Physiology of Metabotropic Glutamate Receptors;Pharmacological Reviews;2020-12-23

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