HTS assays for developing the molecular pharmacology of ion channels

Author:

McManus Owen B

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference54 articles.

1. How many drug targets are there?;Overington;Nat Rev Drug Discov,2006

2. Ion channels: from idea to reality;Hille;Nat Med,1999

3. Early evaluation of compound QT prolongation effects: a predictive 384-well fluorescence polarization binding assay for measuring hERG blockade;Deacon;J Pharmacol Toxicol Methods,2007

4. Development of the predictor HERG fluorescence polarization assay using a membrane protein enrichment approach;Piper;Assay Drug Dev Technol,2008

5. MacKinnon R, et al., Voltage sensor domains of voltage-dependent ion channel proteins and uses thereof. 2008: USA.

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