A yeast-based high-throughput screen identifies inhibitors of trypanosomatid HRG heme transporters with potent leishmanicidal and trypanocidal activity

Author:

Cabello-Donayre MaríaORCID,Cabello-Donayre Irene,Guerra Diego,Orrego Lina M.,Morales Juan C.ORCID,Cautain Bastien,Vicente FranciscaORCID,Pérez-Victoria José M.ORCID

Funder

European Commission

FEDER

Fundación MEDINA

Junta de Andalucía

Publisher

Elsevier BV

Reference37 articles.

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3. Remarques sur la nutrition des Trypanosomides et des bactéries parahémotrophes le “fer actif” de baudisch;Lwoff;Ann Inst Pasteur,1933

4. Bourguignon SC Heme metabolism as a therapeutic target against protozoan parasites;Lechuga;J Drug Target,2019

5. Heme uptake by Leishmania amazonensis is mediated by the transmembrane protein LHR1;Huynh;PLoS Pathogens,2012

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