The Rate-limiting Step of DNA Synthesis by DNA Polymerase Occurs in the Fingers-closed Conformation
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference44 articles.
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2. Motions of the fingers subdomain of klentaq1 are fast and not rate limiting: implications for the molecular basis of fidelity in DNA polymerases;Rothwell;Mol. Cell,2005
3. Fingers-closing and other rapid conformational changes in DNA polymerase I (Klenow fragment) and their role in nucleotide selectivity;Joyce;Biochemistry,2008
4. Single-molecule and ensemble fluorescence assays for a functionally important conformational change in T7 DNA polymerase;Luo;Proc. Natl. Acad. Sci. U. S. A.,2007
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