Dissecting Specificity in the Janus Kinases: The Structures of JAK-Specific Inhibitors Complexed to the JAK1 and JAK2 Protein Tyrosine Kinase Domains

Author:

Williams Neal K.,Bamert Rebecca S.,Patel Onisha,Wang Christina,Walden Patricia M.,Wilks Andrew F.,Fantino Emmanuelle,Rossjohn Jamie,Lucet Isabelle S.

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference47 articles.

1. tyk2, prototype of a novel class of non-receptor tyrosine kinase genes;Firmbach-Kraft;Oncogene,1990

2. JAK2, a third member of the JAK family of protein tyrosine kinases;Harpur;Oncogene,1992

3. JAK3: a novel JAK kinase associated with terminal differentiation of hematopoietic cells;Rane;Oncogene,1994

4. Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction;Wilks;Proc. Natl Acad. Sci. USA,1989

5. Structure and function of the protein tyrosine kinases;Wilks;Prog. Growth Factor Res.,1990

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