Identification of Novel Alternative Splicing Events in the Huntingtin Gene and Assessment of the Functional Consequences Using Structural Protein Homology Modelling
Author:
Funder
CHDI
MRC Centre
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference61 articles.
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2. Pathogenic mechanisms in Huntington's disease;Jones;Int Rev Neurobiol,2011
3. Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis;Kim;Proc Natl Acad Sci U S A,2001
4. Tissue-specific proteolysis of Huntingtin (htt) in human brain: evidence of enhanced levels of N- and C-terminal htt fragments in Huntington's disease striatum;Mende-Mueller;J Neurosci,2001
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