The Nt17 Domain and its Helical Conformation Regulate the Aggregation, Cellular Properties and Neurotoxicity of Mutant Huntingtin Exon 1-Reference-Cited by-同舟云学术

The Nt17 Domain and its Helical Conformation Regulate the Aggregation, Cellular Properties and Neurotoxicity of Mutant Huntingtin Exon 1

Published:2021-10 Issue:21 Volume:433 Page:167222
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Vieweg Sophie,Mahul-Mellier Anne-Laure,Ruggeri Francesco S.,Riguet Nathan,DeGuire Sean M.,Chiki Anass,Cendrowska Urszula,Dietler Giovanni,Lashuel Hilal A.

Funder

École Polytechnique Fédérale de Lausanne

CHDI Foundation Los Angeles

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

AbbVie

Société Française de Nutrition

Cure Huntington's Disease Initiative

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference146 articles.

1. The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease;Andrew;Nat. Genetics,1993

2. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes;MacDonald;Cell,1993

3. Trinucleotide repeat length instability and age of onset in Huntington's disease;Duyao;Nat. Genet.,1993

4. De novo expansion of a (CAG)n repeat in sporadic Huntington's disease;Myers;Nat. Genet.,1993

5. Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat;Persichetti;Mol. Med. (Cambridge, Mass),1995

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