Deregulated Splicing Is a Major Mechanism of RNA-Induced Toxicity in Huntington's Disease-Reference-Cited by-同舟云学术

Deregulated Splicing Is a Major Mechanism of RNA-Induced Toxicity in Huntington's Disease

Published:2019-04 Issue:9 Volume:431 Page:1869-1877
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Schilling Judith,Broemer Meike,Atanassov Ilian,Duernberger Yvonne,Vorberg Ina,Dieterich Christoph,Dagane Alina,Dittmar Gunnar,Wanker Erich,van Roon-Mom Willeke,Winter Jennifer,Krauß Sybille

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference38 articles.

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2. Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture;Cooper;Hum. Mol. Genet.,1998

3. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions;Saudou;Cell,1998

4. Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice;Zheng;PLoS Genet.,2010

5. Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism;Thakur;Nat. Struct. Mol. Biol.,2009

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