Germline Humanization of a Non-human Primate Antibody that Neutralizes the Anthrax Toxin, by in Vitro and in Silico Engineering
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference25 articles.
1. “Superhumanized” antibodies: reduction of immunogenic potential by complementarity-determining region grafting with human germline sequences: application to an anti-CD28;Tan;J. Immunol.,2002
2. Use of human germline genes in a CDR homology-based approach to antibody humanization;Hwang;Methods,2005
3. The contribution of somatic hypermutation to the diversity of serum immunoglobulin: dramatic increase with age;Williams;Immunity,2000
4. Humanized antibodies;Harris,1995
5. IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor V-J and V-D-J rearrangement analysis;Giudicelli;Nucleic Acids Res.,2004
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