Affinity Maturation of a Humanized Rat Antibody for Anti-RAGE Therapy: Comprehensive Mutagenesis Reveals a High Level of Mutational Plasticity Both Inside and Outside the Complementarity-Determining Regions-Reference-Cited by-同舟云学术

Affinity Maturation of a Humanized Rat Antibody for Anti-RAGE Therapy: Comprehensive Mutagenesis Reveals a High Level of Mutational Plasticity Both Inside and Outside the Complementarity-Determining Regions

Published:2009-05 Issue:3 Volume:388 Page:541-558
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Finlay William J.,Cunningham Orla,Lambert Matthew A.,Darmanin-Sheehan Alfredo,Liu Xuemei,Fennell Brian J.,Mahon Ciara M.,Cummins Emma,Wade Jason M.,O'Sullivan Cliona M.,Tan Xiang Yang,Piche Nicole,Pittman Debra D.,Paulsen Janet,Tchistiakova Lioudmila,Kodangattil Sreekumar,Gill Davinder,Hufton Simon E.

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

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