Ultra-high Resolution Crystal Structure of HIV-1 Protease Mutant Reveals Two Binding Sites for Clinical Inhibitor TMC114
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference37 articles.
1. New approaches toward anti-HIV chemotherapy;De Clercq;J. Med. Chem.,2005
2. Overview of the effectiveness of triple combination therapy in antiretroviral-naïve HIV-1 infected adults;Barlett;AIDS,2001
3. 3-Year suppression of HIV viremia with indinavir, zidovudine, and lamivudine;Gulick;Ann. Intern. Med.,2000
4. Inhibitors of HIV-1 protease: a major success of structure-assisted drug design;Wlodawer;Annu. Rev. Biophys. Biomol. Struct.,1998
5. Phenotypic and genotypic analysis of clinical HIV-1 isolates reveals extensive protease inhibitor cross-resistance: a survey of over 6000 samples;Hertogs;AIDS,2000
Cited by 130 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. FMO-guided design of darunavir analogs as HIV-1 protease inhibitors;Scientific Reports;2024-02-13
2. Machine learning‐guided design of potent darunavir analogs targeting HIV‐1 proteases: A computational approach for antiretroviral drug discovery;Journal of Computational Chemistry;2024-01-04
3. Design of substituted tetrahydrofuran derivatives for HIV-1 protease inhibitors: synthesis, biological evaluation, and X-ray structural studies;Organic & Biomolecular Chemistry;2024
4. Molecular chameleons in drug discovery;Nature Reviews Chemistry;2023-12-20
5. Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation;European Journal of Medicinal Chemistry;2023-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3