Structural Evidence for an Octameric Ring Arrangement of SARM1

Author:

Sporny Michael,Guez-Haddad Julia,Lebendiker Mario,Ulisse Valeria,Volf Allison,Mim Carsten,Isupov Michail N.,Opatowsky Yarden

Funder

ISF

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference59 articles.

1. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent toll-like receptor signaling;Carty;Nat. Immunol.,2006

2. Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death;Mukherjee;Immunity.,2013

3. SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection;Hou;J. Immunol.,2013

4. MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival;Kim;J. Exp. Med.,2007

5. Experiments on the section of the glossopharyngeal and hypoglossal nerves of the frog, and observations of the alterations produced thereby in the structure of their primitive fibres;Waller;Philos. Trans. R. Soc.,1850

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