Near-Neighbor Interactions in the NS3-4A Protease of HCV Impact Replicative Fitness of Drug-Resistant Viral Variants-Reference-Cited by-同舟云学术

Near-Neighbor Interactions in the NS3-4A Protease of HCV Impact Replicative Fitness of Drug-Resistant Viral Variants

Published:2019-05 Issue:12 Volume:431 Page:2354-2368
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Doncheva Nadezhda T.,Domingues Francisco S.,McGivern David R.,Shimakami Tetsuro,Zeuzem Stefan,Lengauer Thomas,Lange Christian M.,Albrecht Mario,Welsch Christoph

Funder

German Research Foundation

JSPS-DAAD

National Institutes of Allergy and Infectious Diseases

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference61 articles.

1. Proteins as networks: usefulness of graph theory in protein science;Krishnan;Curr. Protein Pept. Sci.,2008

2. Genetic barrier and variant fitness in hepatitis C as critical parameters for drug resistance development;Welsch;Drug Discov. Today Technol.,2014

3. Evolution of treatment-emergent resistant variants in telaprevir phase 3 clinical trials;Sullivan;Clin. Infect. Dis.,2013

4. Analysis of long-term persistence of resistance mutations within the hepatitis C virus NS3 protease after treatment with telaprevir or boceprevir;Susser;J. Clin. Virol.,2011

5. Virology analyses of HCV isolates from genotype 1-infected patients treated with simeprevir plus peginterferon/ribavirin in phase IIb/III studies;Lenz;J. Hepatol.,2015

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