Robust Antibody–Antigen Complexes Prediction Generated by Combining Sequence Analyses, Mutagenesis, In Vitro Evolution, X-ray Crystallography and In Silico Docking-Reference-Cited by-同舟云学术

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Robust Antibody–Antigen Complexes Prediction Generated by Combining Sequence Analyses, Mutagenesis, In Vitro Evolution, X-ray Crystallography and In Silico Docking

Published:2015-08 Issue:16 Volume:427 Page:2647-2662
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Loyau Jérémy,Didelot Gérard,Malinge Pauline,Ravn Ulla,Magistrelli Giovanni,Depoisier Jean-François,Pontini Guillemette,Poitevin Yves,Kosco-Vilbois Marie,Fischer Nicolas,Thore Stéphane,Rousseau François

Funder

Boninchi Foundation

Schmidheiny Foundation

Swiss National Science Foundation R'equip

Ligue Genevoise Contre le Cancer

University of Geneva

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference41 articles.

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2. Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen;Chen;J Mol Biol,1999

3. Structural basis of signaling blockade by anti-IL-13 antibody Lebrikizumab;Ultsch;J Mol Biol,2013

4. Epitope mapping of inhibitory antibodies targeting the C2 domain of coagulation factor VIII by hydrogen–deuterium exchange mass spectrometry;Sevy;J Thromb Haemost,2013

5. Defining epitopes: it's not as easy as it seems;Greenspan;Nat Biotechnol,1999

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