Crystal Structures of Ternary Complexes of MEF2 and NKX2–5 Bound to DNA Reveal a Disease Related Protein–Protein Interaction Interface

Author:

Lei Xiao,Zhao Jun,Sagendorf Jared M.,Rajashekar Niroop,Xu Jiang,Dantas Machado Ana Carolina,Sen Chandani,Rohs Remo,Feng Pinghui,Chen Lin

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference82 articles.

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2. Control of skeletal muscle-specific transcription: involvement of paired homeodomain and MADS domain transcription factors;Duprey;Int. J. Dev. Biol.,1994

3. The MADS-box family of transcription factors;Shore;Eur. J. Biochem.,1995

4. MEF2: a central regulator of diverse developmental programs;Potthoff;Development,2007

5. S. Nagel, M. Kaufmann, H.G. Drexler, R.A.F. MacLeod, The cardiac homeobox gene NKX2–5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t(5;14)(q35.1;q32.2), Cancer Res. 63 (2003) 5329–5334.

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