Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain-Reference-Cited by-同舟云学术

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Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain

Published:2019-03 Issue:5 Volume:431 Page:885-903
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Ultsch M.,Li W.,Eigenbrot C.,Di Lello P.,Lipari M.T.,Gerhardy S.,AhYoung A.P.,Quinn J.,Franke Y.,Chen Y.,Kong Beltran M.,Peterson A.,Kirchhofer D.

Funder

National Institutes of Health

NIH-ORIP HEI

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference82 articles.

1. PCSK9: a key modulator of cardiovascular health;Seidah;Circ. Res.,2014

2. The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation;Seidah;Proc. Natl. Acad. Sci. U. S. A.,2003

3. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia;Abifadel;Nat. Genet.,2003

4. Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9;Cohen;Nat. Genet.,2005

5. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease;Cohen;N. Engl. J. Med.,2006

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Insights into PCSK9-LDLR Regulation and Trafficking via the Differential Functions of MHC-I Proteins HFE and HLA-C;Cells;2024-05-17

2. Targeting PCSK9 to tackle cardiovascular disease;Pharmacology & Therapeutics;2023-09

3. Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels;Molecular Metabolism;2023-01

4. Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: functional regulation of LDLR levels;2022-10-21

5. Pathogenic gain-of-function mutations in the prodomain and C-terminal domain of PCSK9 inhibit LDL binding;Frontiers in Physiology;2022-09-14

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