What Makes Ras an Efficient Molecular Switch: A Computational, Biophysical, and Structural Study of Ras-GDP Interactions with Mutants of Raf-Reference-Cited by-同舟云学术

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What Makes Ras an Efficient Molecular Switch: A Computational, Biophysical, and Structural Study of Ras-GDP Interactions with Mutants of Raf

Published:2010-06 Issue:3 Volume:399 Page:422-435
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Filchtinski Daniel,Sharabi Oz,Rüppel Alma,Vetter Ingrid R.,Herrmann Christian,Shifman Julia M.

Funder

Israeli Ministry of Health

Forschungsgemeinschaft

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference61 articles.

1. The dark side of Ras: regulation of apoptosis;Cox;Oncogene,2003

2. Understanding Ras: 'it ain't over 'til it's over';Shields;Trends Cell Biol.,2000

3. The GTPase superfamily: a conserved switch for diverse cell functions;Bourne;Nature,1990

4. The GTPase superfamily: conserved structure and molecular mechanism;Bourne;Nature,1991

5. Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity;Morrison;Proc. Natl Acad. Sci. USA,1988

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