Gamma-Secretase Inhibitors Downregulate the Profibrotic NOTCH Signaling Pathway in Recessive Dystrophic Epidermolysis Bullosa-Reference-Cited by-同舟云学术

Gamma-Secretase Inhibitors Downregulate the Profibrotic NOTCH Signaling Pathway in Recessive Dystrophic Epidermolysis Bullosa

Published:2024-07 Issue:7 Volume:144 Page:1522-1533.e10
ISSN:0022-202X
Container-title:Journal of Investigative Dermatology
language:en
Short-container-title:Journal of Investigative Dermatology

Author:

Condorelli Angelo Giuseppe^ORCID,Nobili Rebecca^ORCID,Muglia Anita^ORCID,Scarpelli Giorgia^ORCID,Marzuolo Elisa^ORCID,De Stefanis Cristiano^ORCID,Rota Rossella^ORCID,Diociaiuti Andrea^ORCID,Alaggio Rita^ORCID,Castiglia Daniele^ORCID,Odorisio Teresa^ORCID,El Hachem May^ORCID,Zambruno Giovanna^ORCID

Funder

Ministero della Salute

Debra International

Dystrophic Epidermolysis Bullosa Research Association

DEBRA Austria

Publisher

Elsevier BV

Reference102 articles.

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2. Thrombospondin-1 is a major activator of TGF-beta signaling in recessive dystrophic epidermolysis bullosa fibroblasts;Atanasova;J Invest Dermatol,2019

3. Epidermolysis bullosa;Bardhan;Nat Rev Dis Primers,2020

4. Pro-inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang-(1–7);Bernasconi;EMBO Mol Med,2021

5. Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans;Bielesz;J Clin Invest,2010

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1. A Top-Notch Target;Journal of Investigative Dermatology;2024-07