Mechanism of Protein Kinase B Activation by Insulin/Insulin-Like Growth Factor-1 Revealed by Specific Inhibitors of Phosphoinositide 3-Kinase—Significance for Diabetes and Cancer
Author:
Publisher
Elsevier BV
Subject
Pharmacology (medical),Pharmacology
Reference181 articles.
1. Phosphatidylinositol 3-kinase related kinases;Abraham;Curr. Opin. Immunol.,1996
2. Assessment of the roles of mitogen-activated protein kinase, phosphatidylinositol 3-kinase, protein kinase B, and protein kinase C in insulin inhibition of cAMP-induced phosphoenolpyruvate carboxykinase gene transcription;Agati;J. Biol. Chem.,1998
3. The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential;Ahmed;Oncogene,1993
4. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase;Ahmed;Proc. Natl. Acad. Sci. USA,1997
5. Mechanism of activation of protein kinase B by insulin and IGF-1;Alessi;EMBO J.,1996
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