Efficacy of a food supplement based on S-adenosyl methionine and probiotic strains in subjects with subthreshold depression and mild-to-moderate depression: A monocentric, randomized, cross-over, double-blind, placebo-controlled clinical trial

Author:

Ullah Hammad,Di Minno Alessandro,Esposito Cristina,El-Seedi Hesham R.,Khalifa Shaden A.M.,Baldi Alessandra,Greco Agostino,Santonastaso Salvatore,Cioffi Valeria,Sperandeo Raffaele,Sacchi Roberto,Daglia MariaORCID

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference63 articles.

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2. WHO, Depression, (2021). https://www.who.int/news-room/fact-sheets/detail/depression (Accessed 25 May 2022).

3. Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic;Santomauro,2020

4. Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019;Yang;Epidemiol. Psychiatr. Sci.,2021

5. Prevalence of anxiety during the COVID-19 pandemic: a systematic review and meta-analysis of over 2 million people;Delpino;J. Affect. Disord.,2022

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