Metabolite profiling of traditional Chinese medicine XIAOPI formula: An integrated strategy based on UPLC-Q-Orbitrap MS combined with network pharmacology analysis

Author:

Wang Neng,Yang Bowen,Zhang Juping,Zheng Yifeng,Wang Shengqi,Zhang Xiaotong,Situ Honglin,Lin Yi,Wang Zhiyu

Funder

the National Natural Science Foundation of China

Guangdong Science and Technology Department

Guangdong High-level Personnel of Special Support Program

Department of Education of Guangdong Province

Traditional Chinese Medicine Bureau of Guangdong Province

the PhD Start-up Fund of Natural Science Foundation of Guangdong Province

Science and Technology Planning Project of Guangdong Province

Guangzhou Municipal Science and Technology Project

the Specific Research Fund for TCM Science and Technology of Guangdong provincial Hospital of Chinese Medicine

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference32 articles.

1. The clinical research of "Xiaopi" oral liquids in reversing precancerosis of breast and affecting the secretion of E2 and P in Luteal Phase;Situ;Chinese Journal of Cancer Prevention and Treatment,2002

2. The effects of Xiaopi Granules on the mastoplasia model of rats;Meng;Pharmacology and Clinics of Chinese Materia Medica,2005

3. The effects of Xiaopi Granules on of the rabbit mastoplasia model;Chen;Qilu Pharmaceutical Affairs,2007

4. The effect of“xiaopi granule”on the SD rate pre-cancerosis models and on the pathway of EGFR-STAT3;Chen;Journal of Liaoning University of Traditional Chinese Medicine,2012

5. Network-pharmacology-based validation of TAMS/CXCL-1 as key mediator of XIAOPI formula preventing breast cancer development and metastasis;Wang;Sci. Rep.,2017

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