Prediction of the pharmacokinetics and pharmacodynamics of topiroxostat in humans by integrating the physiologically based pharmacokinetic model with the drug-target residence time model-Reference-Cited by-同舟云学术

Prediction of the pharmacokinetics and pharmacodynamics of topiroxostat in humans by integrating the physiologically based pharmacokinetic model with the drug-target residence time model

Published:2020-01 Issue: Volume:121 Page:109660
ISSN:0753-3322
Container-title:Biomedicine & Pharmacotherapy
language:en
Short-container-title:Biomedicine & Pharmacotherapy

Author:

Luo Zhiqiang,Yu Guohua,Han Xing,Yang Tingting,Ji Yanhua,Huang Huating,Wang Guopeng,Liu Yang,Sun Wenyan

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference35 articles.

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3. Renoprotective effect of the xanthine oxidoreductase inhibitor Topiroxostat under decreased angiotensin II type 1a receptor expression;Ohata;Eur. J. Pharmacol.,2017

4. Cross-over trial of Febuxostat and topiroxostat for hyperuricemia with cardiovascular disease (TROFEO trial);Sezai;Circ. J.,2017

5. Effects, safety, and plasma levels of topiroxostat and its metabolites in patients receiving hemodialysis;Oyama;Ren. Replace. Ther.,2016

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