A novel GPR119 agonist DA-1241 preserves pancreatic function via the suppression of ER stress and increased PDX1 expression-Reference-Cited by-同舟云学术

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A novel GPR119 agonist DA-1241 preserves pancreatic function via the suppression of ER stress and increased PDX1 expression

Published:2021-12 Issue: Volume:144 Page:112324
ISSN:0753-3322
Container-title:Biomedicine & Pharmacotherapy
language:en
Short-container-title:Biomedicine & Pharmacotherapy

Author:

Kim Mi-Kyung,Cheong Ye Hwang,Lee Seung Ho,Kim Tae Hyoung,Jung Il Hoon,Chae Yuna,Lee Jeong-Ha,Yang Eun Kyoung,Park Hansu,Yang Jae-Sung,Hong Ki Whan

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference45 articles.

1. A role for β-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release;Chu;Endocrinology,2007

2. Type 2 diabetes: new genes, new understanding;Prokopenko;Trends Genet,2008

3. Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes;Laybutt;Diabetologia,2007

4. Oxidative and endoplasmic reticulum stress in β-cell dysfunction in diabetes;Hasnain;J. Mol. Endocrinol.,2016

5. A role for intestinal endocrine cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucagon-Like peptide-1 and glucose-dependent insulinotropic peptide release;Chu;Endocrinology,2008

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Advances in small-molecule insulin secretagogues for diabetes treatment;Biomedicine & Pharmacotherapy;2024-09

2. Investigational new drug approval of DA-1241: what we know about GPR119 targeting for MASH therapy?;Expert Opinion on Investigational Drugs;2024-08-07

3. GPR119 agonists for type 2 diabetes: past failures and future hopes for preclinical and early phase candidates;Expert Opinion on Investigational Drugs;2024-02-23

4. Structural Insight on GPR119 Agonist as Potential Therapy for Type II Diabetes: A Comprehensive Review;Mini-Reviews in Medicinal Chemistry;2023-11

5. GPR119 activation by DA-1241 alleviates hepatic and systemic inflammation in MASH mice through inhibition of NFκB signaling;Biomedicine & Pharmacotherapy;2023-10

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