Panax quinquefolium saponin inhibits endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and attenuates the progression of osteoarthritis in rat

Author:

Xie Jun-Jun,Chen Jian,Guo Shi-Kun,Gu Yun-Tao,Yan Ying-Zhao,Guo Wei-Jun,Yao Cheng-lun,Jin Meng-Yun,Xie Cheng-Long,Wang Xiang,Wang Xiang-Yang,Chen Long

Funder

Zhejiang province science and technology hall

Zhejiang Provincial Health Department Foundation of China

Zhejiang Traditional Chinese Medicine Bureau Foundation of China

National Nature Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference52 articles.

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2. Osteoarthritis: a disease of the joint as an organ;Loeser;Arthritis Rheum.,2012

3. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis;Kapoor;Nat. Rev. Rheumatol.,2011

4. In vivo studies of cartilage regeneration after damage induced by catabolin/interleukin-1;Page Thomas;Ann. Rheum. Dis.,1991

5. Arthritogenic actions of recombinant IL-1 and tumour necrosis factor alpha in the rabbit: evidence for synergistic interactions between cytokines in vivo;Henderson;Clin. Exp. Immunol.,1989

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